Kristóf Molnár1, Ákos Gábor Emri1, Constantinos Voniatis1, Rita Varga1, Zoltán Kiss2, Miklós Zrínyi1, Angéla Jedlovszky-Hajdú1
1 Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Budapest
2 Department of Polymer Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest
Introduction: In the assessment of the mechanical properties of suturable implants, the weakest link, namely the suture-implant connection is often overlooked, even though the load is born mostly by these connections. As there are many newly developed materials and implants all over the world, it is important to give a new mechanical model for the assessment of mechanical properties of sutured implants.
Aim: It was in our aim to develop a mechanical model for the evaluation of the mechanical properties of sutured cylindrical implants and also create a mathematical model describing it.
Method: As samples, electrospun poly(vinyl alcohol) membranes (developed by the Laboratory of Nanochemistry), commercially available latex rubber bands and a standard poly(propylene) hernia mesh were used. Disks of different diameters were cut from the samples and fixed with simple running suture inside a tube of 100 mm in diameter. Indentation was carried out with custom made head (a spherical stainless steel sphere) pressed into the center of the samples using an Instron 4942 Mechanical tester.
Results: The developed mechanical test method provided adequate information regarding the suturability and surgical performance of the samples involved. From the collected force-displacement data the standard mechanical performance of the samples was also obtained. Further, the comparison of different samples in different setups became possible by the aid of the mathematical model.
Conclusion: The developed mechanical model provides new information on the performance of sutured implants, which, if carried out prior to in vivo experiments, significantly decreases the chance of mechanical failure of the materials during or after surgery.
Doctoral School: Basic Medicine
Program: Cellular and Molecular Biophysics
Supervisor: Angéla Jedlovszky-Hajdú
E-mail address: email@example.com