László Márk Czumbel1,
1 Department of Oral Biology, Semmelweis University, Budapest
Introduction: Since Branemark introduced machined endosseous dental implants in 1986, numerous studies have shown that surface roughness has an important role in enhancing osseointegration. Sand-blasting is a common surface modification that is used currently to improve osseointegration. There are randomized clinical trials (RCTs) to improve osseointegration, however the validity of the results is arguable, because of small sample numbers.
Aims: To investigate the difference in marginal bone loss (MBL) and implant failure (IF) between machined and sand-blasted dental implants conducting meta-analysis.
Method: Meta-analysis was conducted according to the PRISMA protocol. The electronic search was performed in Cochrane, Embase and Pubmed, with no time restriction. Eligibility criteria included: English language, participants with no systemic diseases, nor heavy smoking, nor excessive alcohol consumption. Data of MBLs and IF were extracted and synthesized from each study. Bias of the studies was evaluated according to The Cochrane Risk of Bias Tool. Pooled event rate, risk-ratio and mean difference were calculated. Random effect model was applied at all of analyses with DerSimonien-Laird estimation. Statistical heterogeneity was analyzed using the I2 and the chi-squared test to gain probability-values; p<0.10 was defined to indicate significant heterogeneity. Subgroups by years were created in the analysis. Statistical analyses were performed with Comprehensive Meta-Analysis Software (CMA).
Results: Literature search reviled 182 records without duplicates. Out of these articles five met eligibility criteria, these were included in the data synthesis. The results indicate a significant difference (p=0.022) of IF between turned and sand-blasted implants. In contrast, no significant difference (p=0.654) was seen between MBLs when turned and sand-blasted implants were compared.
Conclusion: This meta-analysis reveals that there is no significant difference in MBL between machined and sand-blasted implants. On the other hand, there is significant and important difference in IF between the different implant surfaces in favor of the sand-blasted ones.
Doctoral School: Clinical Medicine
Program: Dental Research
Supervisor: Gábor Varga
E-mail address: firstname.lastname@example.org