Eszter Kenézlői 1, Lívia Balogh 1, Kata Fazekas 1, Zsófia Nemoda 2, Emese Kruk 1,2, Zsolt Unoka 1, János Réthelyi 1
1. Department of Psychiatry and Psychotherapy. Semmelweis University, Budapest
2. Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest
Introduction High level of impulsivity is a core feature of different psychiatric conditions: ADHD, BPD, disruptive impulse control and conduct disorders, bulimia nervosa, other maladaptive behaviors, like non-suicidal self-harm, suicidal behavior, different addictions.
Aims Our aim is to carry out a trans-diagnostic study of impulsivity as a common risk factor, taking into consideration the different domains of impulsivity (motor, attentional, nonplanning). It investigates inhibitory control neurocognitive deficits, childhood adversities and genetic vulnerability factors in the background of impulsivity.
Method In this poster presentation, we intorduce the results of our pilot study which aims to compare the impulsivity profile and personality traits of patients with aADHD, BPD main diagnoses and control subjects, based on self report questionnaires. N=72 patients with aADHD, N=40 patients with BPD and N=31 control persons have been involved and besides impulsivity domains, we have carried out analyses on the role of childhood adverse events in the background of impulsivity. At this point of data collection, there is a predominance of female participants in the BPD group, thus we have checked our results by including only females in the analyses.
Results Comparing the three groups significant differences can be described between each impulsivity domains: higher level attentional and motor impulsivity are present in aADHD, while nonplanning impulsivity is more characteristic to BPD. Excluding males from the analyses, the same pattern was present. Using Cloninger temperament and character inventory, aADHD patients reached significant higher levels on each subscale (novelty seeking, harm avoidance, reward dependency, perseverance, selfdirection, transcendency) but not as high as the controls.
Conclusion Impulsivity, as a diagnostic criterion of different psychiatric disorders, is a heterogenous phenomenon. It has different characteristics according to the condition it is a part of. Studying impulsivity can help to understand the etiology of different psychiatric conditions, which can result in more specific therapeutic interventions.
Doctoral School: Mental Health Sciences
Supervisor: Prof. János Réthelyi