PhD Scientific Days 2021

CL_VII_L: Clinical Medicine VII. Lectures

Comparative Study Between the Auditory and Vestibular Functions in Ménière’s Disease

Text of the abstract

Introduction: Ménière’s disease (MD) is a disturbance in both the vestibular and the cochlear functions. Investigation methods to verify the disturbances include subjective and objective registrations.
Aims: To assess the relationship between the loss of the cochleovestibular functions in MD.
Methods: Forty-three patients with definite MD underwent pure-tone audiometry (PTA) and caloric test. Canal paresis (CP%), dPTA (interaural difference of hearing level), and average PTA results were contrasted. IBM SPSS V24 was used for statistical analysis.
Result: According to the diagnostic criteria of PTA of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) the MD, most patients were in stage C, and caloric weakness was found in 29 patients. Linear (R2 = 0.06) and nonlinear correlation tests (rho = 0.245, P = 0.113) between canal paresis (CP%) and dPTA showed no correlation, as well as between CP% and PTA analysis (R2 = 0.007, rho = 0.11, P = 0.481). As per the categorial analysis, no correlation was detected between the groups either (k = 0.174, 95% CI: 0.0883 - 0.431).
Conclusion and Funding: Based on the results of the analysis, it was concluded that a more advanced stage determined by audiometry does not indicate increasing values in the CP% parameter. Therefore, audiometric changes do not directly correspond with the vestibular ones; consequently no specific correlation exists between them. Thus, for therapy planning and diagnosis, both tests are necessary.

University and Doctoral School

Semmelweis University, Károly Rácz Doctoral School of Clinical Medicine