PhD Scientific Days 2026

Poster Session 2.K - Mental Health Sciences

The Importance of Frailty in Anticipating Post Intensive Care Syndrome

Name of the presenter

Élő, László Gergely

Institute/workplace of the presenter

Semmelweis University Department of Intensive Therapy

Authors

Dr. Élő László Gergely¹, Dr Zubek László¹, Dr. Szűcs Orsolya¹, Benkovics Edit MSC¹, Dr. Élő Gábor¹, Prof. Dr. Molnár Zsolt¹
1: Semmelweis University Department of Intensive Therapy

Text of the abstract

Introduction
We have conducted a single-centre prospective observational study at the Semmelweis University Department of Intensive Therapy. We focused on post-intensive care syndrome (PICS), quality of life, and their correlation with frailty and acute illness severity at admission.
Materials and Methods
We conducted our study on 245 patients admitted to two ICUs in our department, with diverse aetiologies and pre-hospitalisation histories. Exclusion criteria were death or discharge before 24 hours of ICU care. At admission, we recorded the Clinical Frailty Scale (CFS), APACHE II, and SAPS II scores. At 3 months after discharge, EuroQoL 5D5L was collected via telephone interview among 103 of 112 survivors. At 12 months, EQ-5D, SF-36 QoL survey, MMS, and Beck Depression Inventory were collected during a personal interview, with 45 respondents out of 97 survivors.
Results
Compared with validated population studies of Hungary, our patients have shown below-average scores in General Health, Physical Role Impairment, and Mental Health. We observed above-average scores in Bodily Pain, Social Functioning, Vitality and Emotional Role Impairment dimensions. The average EQ5D index was 0.92 at 3 months and 0.84 at 12 months. MMS test showed no cognitive impairment. U tests suggested a strong correlation between Physical Functioning and CFS, General Health and APACHE/SAPS-II. Pain, Social Function, Emotional Role Impairment and EQ5D correlated with all three. ROC analysis has shown AUC > 0.7 for CFS, Physical functioning, and the one-year EQ5D index.
Conclusions
Contrary to the established literature, we have observed that our patients' long-term QoL is not significantly worse than that of the general population and that there is a strong statistical correlation between frailty and acute illness severity at admission and eventual QoL. We have failed to show a significant predictive value for any of the observed SF-36 parameters for eventual QoL.