PhD Scientific Days 2026

Poster Session 2.G - Pharmaceutical Sciences and Health Technologies

Nanotechnology Application and Its Significance for Personalized Functional Dietary Supplements and Foods

Name of the presenter

Pásztorné Benyó, Zsuzsanna

Institute/workplace of the presenter

Semmelweis University/ Pharmaceutical Sciences and Health Technologies Division/ Center for Translational Medicine

Authors

Zsuzsanna Pasztorne Benyo^1,2, Dr. Renáta Papp, MD, PhD^2,3,4,5, Dr. Marie Anne Engh, MD, PhD², Dr. Diána Balogh-Weiser, PhD⁶, Dr. Ferenc Ender, PhD⁶, Zoltán Nagy^2,7
1: Semmelweis University, Pharmaceutical Sciences and Health Technologies Division
2: Semmelweis University, Center for Translational Medicine
3: Semmelweis University, Department of Pharmacology and Pharmacotherapy
4: Semmelweis University, Center for Pharmacology and Drug Research & Development
5: Semmelweis University, Department of Aviation and Space Medicine
6: Budapest Technical University
7: Semmelweis University, Department of Health Sciences

Text of the abstract

Introduction
Long-duration space missions require stable and nutrient-dense food systems capable of maintaining nutritional quality under extreme environmental conditions. Biomass-derived nutrients, such as proteins and antioxidants from microalgae (e.g., Spirulina), are promising sources of sustainable nutrition; however, these compounds are highly susceptible to degradation during processing and storage. Nanofiber-based encapsulation technologies, particularly electrospinning, may improve nutrient stability and enable controlled release.
Aims
This research aims to investigate whether nanofiber-based encapsulation enhances nutrient stability and controlled release of biomass-derived nutrients compared with their non-encapsulated forms, and to evaluate the potential of electrospinning to improve the stability and functionality of Spirulina-based biomasses.
Methods
The project combines a systematic literature review and laboratory research. The systematic review follows Cochrane methodology and a PICO framework, assessing studies on biomass-derived nutrients and nanofiber-based encapsulation technologies. Structured searches were completed in PubMed, Scopus, and Web of Science. In parallel, laboratory experiments investigate electrospun Spirulina formulations, assessing protein stability, antioxidant properties, and release characteristics under controlled conditions.
Result
Data collection and experimental preparation are currently in progress. Results will be available by the time of the PhD Scientific Days Conference, in June 2026.
Conclusion
This research is expected to provide evidence on the potential of nanotechnology-based encapsulation strategies to enhance nutrient stability and functionality of biomass-derived foods, contributing to the development of sustainable nutrition solutions for space missions and extreme terrestrial environments.
Funding; Supported by the Semmelweis University Research, Development and Innovation Fund.
EKÖP-KDP – Cooperative Doctoral Program, Semmelweis University.